- 5Closed nowAfterlife Video Game Lounge101 Wyndham Street North, Guelph, ON N1H 4E9Bar Night club
- Base Nightclub10 Wyndham Street North, Guelph, ON N1H 4E3Bar Night club
- 3.8Closed nowDoogie's & Pablo's37 Wyndham Street North, Guelph, ON N1H 4E4Bar Night club
- 5Closed nowManhattans951 Gordon Street, Guelph, ON N1G 4S1Restaurant Bar Night club
- Noel's Dope Poker Pizzeria20 Weir Drive, Guelph, ON N1C 1E6Night club
- 4.7Opus Lounge92 Macdonell Street, Guelph, ON N1H 4E5Night club
- 1.4Closed nowPalace Night Club100 Carden Street, Guelph, ON N1H 4E3Bar Night club
- Partytown100 Carden Street, Guelph, ON N1H 3A3Night club
- 4Closed nowRobusta Cafe & Lounge160 Macdonell Street #101b, Guelph, ON N1H 2Z6Restaurant Bar Cafe Night club
- 4.4Closed nowSymposium Cafe Restaurant & Lounge304 Stone Road West, Guelph, ON N1GRestaurant Bar Cafe Night club
- 3TABU Nightclub96 Macdonell Street, Guelph, ON N1H 4E5Bar Night club
- 4.6Closed nowThe Boardroom - Guelph's Game Cafe99 Wyndham Street North, Guelph, ON N1H 4E9Bar Cafe Night club
- 1.2Closed nowTrappers Alley100 Carden Street, Guelph, ON N1H 4E3Night club
- 3.8Van Gogh's Ear10 Wyndham Street North, Guelph, ON N1HBar Night club
- Closed nowVoodoo Vapes Apothecary & Vaporium765A Woolwich Street, Guelph, ON N1H 3Z2Bar Night club